Nitroimidazole family of antibiotics(eg. Metronidazole(flagyl)) and alcohol:
The effect of the alcohol will be increased exponentially, also serious body reaction that can lead to shock can occur.
Insulin and Beta blockers in diabetic patients
Insulin overdose usually results in dangerously low blood sugar with tremors as it’s main symptom. Using Insulin with beta blockers (which are used to treat tremor) makes it harder to know when this is happening and could result in the death of the patient.
Paracetamol and alcohol
Each of these drugs on its own requires heavy duty metabolism and harm the liver. Paracetamol breakdown by the liver, first produces a metabolite that is toxic to the liver before going on to break it down to it’s excretory form.
It takes the liver approximately 17 hours to completely metabolise just 500ml of standard alcohol, this is too much pressure and work all at once. So do well to avoid either, and most importantly both of them together.
Aspirin and another NSAID( eg. Ibuprofen, diclofenac)
Your chances of having Stomach bleeding is greatly increased with either of them; when combined together or taken within 8 hours of each other, It’s almost certain that you’d develop severe and possibly fatal stomach bleeding.
Combination of ACE inhibitors with potassium-sparing diuretics such as amiloride in patients with heart disorders can increase potassium retention so strongly that life-threatening hyperkalemia ensues.
Antibiotics reduce the effectiveness of Oral contraceptives
Use backup protection if you are on the pill and need to take an antibiotic.
Courtesy of: Iloabuchi Francis C.